0.3%
Retinaldehyde
Encapsulated in HPR matrix; closest off-the-shelf molecule to Rx tretinoin.
Actives · Retinoid Serum
0.3% encapsulated retinaldehyde + 0.2% HPR — buffered to pH 5.5
Retinaldehyde is one chemical step away from Rx tretinoin and converts faster than retinol — with a measurably lower irritation profile. We use it at 0.3%, encapsulated for shelf stability and slow release.
Free US shipping over $50 · 60-day risk-free returns · Ships same-day if ordered by 2pm PT
Retinoic acid (the molecule in Rx tretinoin) is the form that actually does the work on your skin. Most over-the- counter retinoids — retinol, retinyl palmitate — have to convert two or three steps before they reach retinoic acid. Each conversion loses potency.
Retinaldehyde sits one step away. It converts to retinoic acid faster, at a higher conversion rate, with measurably lower irritation than retinol at equivalent strength. The formulation literature has been consistent on this point since the 1990s.
We use it at 0.3% — the upper end of the published clinical range — encapsulated in a hydroxypinacolone matrix that keeps the molecule stable in the bottle and releases it slowly into the skin.
Week 1–2: Apply 2–3 pumps to clean, dry skin three evenings a week. Follow with the Cushion Cream Light or Ceramide Recovery Balm.
Week 3–4: Build to four evenings a week.
Week 5+: Nightly, as tolerated. Always finish with SPF 30+ in the morning.
Pairs well on alternate evenings with Tranexamic Brightening Serum (pigmentation work) and Peptide Repair Concentrate (collagen support).
Aqua, Squalane, Glycerin, Hydroxypinacolone Retinoate, Retinaldehyde, Bisabolol, Tocopherol, Sodium Hyaluronate, Glycerin, Pentylene Glycol, Allantoin, Panthenol, Sodium PCA, Xanthan Gum, Phenoxyethanol, Ethylhexylglycerin.
Free US shipping on orders over $50. Standard delivery 3–5 business days. Expedited 2-day and overnight at checkout. Every package carbon-offset through the Climate Neutral program.
Try Vellum risk-free for 60 days. If your skin doesn’t love it, email hello@vellumbeauty.co for a full refund — even if the bottle is empty. No return shipping needed.
Listed on the bottle
Every Vellum bottle lists the percentage of every active on the front. If a molecule is below the studied threshold, it doesn’t go in.
0.3%
Encapsulated in HPR matrix; closest off-the-shelf molecule to Rx tretinoin.
0.2%
Ester-stable retinoid; supports the aldehyde without stacking irritation.
0.5%
Chamomile-derived; calms visible redness from the active.
Vehicle
Bioidentical lipid; restores barrier disturbed by retinoid conversion.
Start slow, build up
The retinoid your skin actually tolerates is the one you stay on. Build slowly. We’ll be in your inbox at weeks 2, 4, and 8 with check-ins.
After cleansing, press two pumps into damp skin. Follow with Cushion Cream Light. Skip nights where skin feels reactive — this isn’t a race.
Skin should feel calm by now. Move to four nights and introduce the Glass Skin Mask one Sunday for a barrier reset.
As tolerated. Most users land on five to six nights a week and stay there. The bottle lasts roughly 90 days at nightly use.
Non-negotiable. Retinaldehyde works at the dermal layer — unprotected sun exposure undoes the work. Morning Veil SPF 50 is formulated specifically to layer with this routine.
Independent clinical, 12 weeks
91%
measurable improvement in fine lines at 12 weeks
78%
reduction in visible hyperpigmentation at 12 weeks
94%
said they would repurchase at 12 weeks
0%
discontinued for irritation (clinical-grade tolerability)
Independent third-party study, 80 participants ages 28–62, all skin types and Fitzpatrick I–VI. Graded by board-certified dermatologists at weeks 4, 8, and 12. Full study summary available on request.
218 verified reviews
96% would recommend to a friend
I’ve tried tretinoin, adapalene, three brands of retinol — and every single one gave me a six-week flare. This one didn’t. Three nights a week for two months, then nightly, and the lines around my eyes are visibly softer. The amber pump is also a small luxury every evening.
Mira L.
Verified buyer · 30 mL · 14 weeks of use
I bought this because the dermatologist I see at UCSF mentioned 0.3% retinaldehyde is the dose the formulation literature supports. I was skeptical at $92. After eight weeks: fewer breakouts, brighter cheeks, no peeling. I will be repurchasing.
Jordan M.
Verified buyer · 30 mL · 8 weeks of use
Rosacea-adjacent reactive skin. I patch-tested on my jawline for a week, then went all-in. Zero stinging, zero flushing. The Cushion Cream Light on top makes the whole routine wearable. Wish I’d found this two years ago.
Priya R.
Verified buyer · 30 mL · 10 weeks of use
From our derm advisory panel
“0.3% retinaldehyde, encapsulated, buffered to pH 5.5 — this is the formulation I describe to patients when they ask what they can buy off the shelf that’s honest about its dose. The literature on retinaldehyde tolerability versus retinol is consistent, and Vellum has built around that.”
Dr. Anna Reyes, MD, FAADBoard-Certified Dermatologist · Vellum Clinical Panel
The Vellum Circle
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